Candidate Biomarkers for PTSD Symptoms Identified
Free Articles at end of abstract Alterations in the neurosteroid biosynthetic pathways of veterans of the current conflicts in Iraq and Afghanistan may be associated with multiple symptoms of posttraumatic stress disorder (PTSD), according to an initial biomarker study presented at the American College of Neuropsychopharmacology (ACNP) 48th Annual Meeting.
"Overall, allopregnanolone looks like a particularly promising biomarker that we might use to help assess symptom severity in PTSD and pain disorders, understand their neurobiological underpinnings, develop new treatment options, and predict therapeutic response," Dr. Marx said in a statement.
Additional articles by lead researcher:
1.
Association of trauma exposure with psychiatric morbidity in military veterans who have served since September 11, 2001.
Dedert EA, Green KT, Calhoun PS, Yoash-Gantz R, Taber KH, Mumford MM, Tupler LA, Morey RA, Marx CE, Weiner RD, Beckham JC.
J Psychiatr Res. 2009 Jun;43(9):830-6. Epub 2009 Feb 18.PMID: 19232639 [PubMed - indexed for MEDLINE]
2.
Factorial invariance of posttraumatic stress disorder symptoms across three veteran samples.
McDonald SD, Beckham JC, Morey R, Marx C, Tupler LA, Calhoun PS.
J Trauma Stress. 2008 Jun;21(3):309-17.PMID: 18553409 [PubMed - indexed for MEDLINE]
American College of Neuropsychopharmacology (ACNP) 48th Annual Meeting
SOURCE: MedScape Candidate Biomarkers for PTSD Symptoms Identified by Deborah Brauser. http://www.medscape.com/viewarticle/713642?src=rss