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fMRI: Applications in Cognitive Neuroscience

 fMRI: Applications in Cognitive Neuroscience – Springer Protocols

Abstract

Neuroimaging has, in many respects, revolutionized the study of cognitive neuroscience, the discipline that attempts to determine the neural mechanisms underlying cognitive processes. Early studies of brain–behavior relationships relied on a precise neurological exam as the basis for hypothesizing the site of brain damage that was responsible for a given behavioral syndrome.

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Molecular mechanisms of Posttraumatic Stress Disorder

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Impaired semantic memory in the formation and maintenance of delusions post-traumatic brain injury: a new cognitive model of delusions

Impaired semantic memory in the formation and maintenance of delusions post-traumatic brain injury: a new cognitive model of delusions

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Rapid, Reversible Modulation of Blood-Brain BarrierP-Glycoprotein Transport Activity by Vascular Endothelial Growth Factor

Cellular/Molecular
Rapid, Reversible Modulation of Blood–Brain BarrierP-Glycoprotein Transport Activity by Vascular Endothelial Growth Factor

Increased brain expression of vascular endothelial growth factor (VEGF) is associated with neurological disease, brain injury, and blood–brain barrier (BBB) dysfunction. However, the specific effect of VEGF on the efflux transporter P-glycoprotein, a critical component of the BBB, is not known.

Using isolated rat brain capillaries and in situ rat brain perfusion, we determined the effect of VEGF exposure on P-glycoprotein activity in vitro and in vivo.